Protein name:
Anthrax toxin receptor 1 ;
Alternative:
Organism:
Rat (Rattus norvegicus).
General Annotation
Sub Unit:
Interacts with gelatin and type 1 collagen. Interacts with the actin cytoskeleton. Binds to the protective antigen (PA) of Bacillus anthracis. Binding does not occur in the presence of calcium.
Function:
Plays a role in cell attachment and migration. Interacts with extracellular matrix proteins and with the actin cytoskeleton. Mediates adhesion of cells to type 1 collagen and gelatin, reorganization of the actin cytoskeleton and promotes cell spreading. Plays a role in the angiogenic response of cultured umbilical vein endothelial cells.
Subcellular Location:
Cell membrane
Single-pass type I membrane protein
Cell projection
lamellipodium membrane
Single-pass type I membrane protein
Cell projection
filopodium membrane
Single-pass type I membrane protein
At the membrane of lamellipodia and at the tip of actin-enriched filopodia. Colocalizes with actin at the base of lamellipodia.
Protein Attributes:
50:
MDRAGRLGTG | LRGLCVAALV | LVCAGQGGRR | EDGGPACYGG | FDLYFILDKS |
100:
GSVLHHWNEI | YYFVEQLAHR | FISPQLRMSF | IVFSTRGTTL | MKLTEDREQI |
150:
RQGLEELQKV | LPGGDTYMHE | GFERASEQIY | YENSQGYRTA | SVIIALTDGE |
200:
LHEDLFFYSE | REANRSRDLG | AIVYCVGVKD | FNETQLARIA | DSKDHVFPVN |
250:
DGFQALQGII | HSILKKSCIE | ILAAEPSTIC | AGESFQVVVR | GNGFRHARNV |
300:
DRVLCSFKIN | DSVTLNEKPF | AVEDTYLLCP | APILKEVGMK | AALQVSMNDG |
350:
LSFISSSVII | TTTHCSDGSI | LAIALLILFL | LLALALLWWF | WPLCCTVIIK |
400:
EVPPPPVEES | EEEDDDGLPK | KKWPTVDASY | YGGRGVGGIK | RMEVRWGEKG |
450:
STEEGAKLEK | AKNARVKMPE | QEYEFPEPRN | LNNNMRRPSS | PRKWYSPIKG |
500:
KLDALWVLLR | KGYDRVSVMR | PQPGDTGRCI | NFTRVKNSQP | AKYPLNNSYH |
550:
SSSPPPAPIY | TPPPPAPHCP | PPAPSAPTPP | IPSPPSTLPP | PPQAPPPNRA |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
Rat
ELISA Kit for Rat Anthrax toxin receptor 1
ELISA Kit for Rat Anthrax toxin receptor 1
ELISA Kit for Rat Anthrax toxin receptor 1
CLIA Kit for Rat Anthrax toxin receptor 1
CLIA Kit for Rat Anthrax toxin receptor 1
CLIA Kit for Rat Anthrax toxin receptor 1
Polyclonal Antibody for Rat Anthrax toxin receptor 1
Polyclonal Antibody for Rat Anthrax toxin receptor 1
Polyclonal Antibody for Rat Anthrax toxin receptor 1
Monoclonal Antibody for Rat Anthrax toxin receptor 1
Monoclonal Antibody for Rat Anthrax toxin receptor 1
Monoclonal Antibody for Rat Anthrax toxin receptor 1
Protein for Rat Anthrax toxin receptor 1
Protein for Rat Anthrax toxin receptor 1
Protein for Rat Anthrax toxin receptor 1
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
"Genetic susceptibility to anthrax lethal toxin in rats."
Nye S.H.
,
Evans D.L.
,
Baye J.
Submitted (2006-06) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
strain :
Brown Norway/Mcwi .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Brain .